Human cardiac catheterization was introduced by Werner Forssman in 1929.
Ignoring his department chief, and tying his assistant to an operating
table to prevent her interference, he placed a ureteral catheter into
a vein in his arm, advanced it to the right atrium [of his heart], and
walked upstairs to the x-ray department where he took the confirmatory
x-ray film. In 1956, Dr. Forssman was awarded the Nobel Prize.